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Surface swabs of the table eggs were carried out using sterile swab sticks. These were inoculated on Mannitol Salt Agar and incubated at 37°C for 24 hours. The isolates obtained were morphologically and biochemically characterized. 62% of the isolates obtained were identified as Staphylococcus aureus. 0.5 McFarland standard of each Staphylococcus aureus isolate was subjected to antibiotic susceptibility test on Muller Hinton Agar using the disc diffusion method. Antibiotic susceptibility was determined by observing and measuring clear zones in millimetres. The antibiogram pattern of Staphylococcus aureus on the surface of table eggs from Ezrad farms located in Iwo, Osun State was investigated. Staphylococcus aureus isolates were 100% resistant to Augmentin and Cloxacillin while resistance to Ceftazidime, Erythromycin, Gentamycin, Ofloxacin, Cefuroxime and Ceftriaxone were at 96%, 89%, 86%, 82%, 75% and 57% respectively. This study shows high resistance of Staphylococcus aureus isolated from eggshells to antibiotics which could pose a serious health problem.
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