Cryptosporidiosis and Associated Risk Factors among Children Attending Paediatric Hospitals in Enugu Metropolis, Enugu State, Nigeria
International Journal of Pathogen Research, Volume 12, Issue 1,
Cryptosporidiosis is a zoonotic disease caused by infection with protozoan parasite of the genus Cryptosporidium. It is associated with moderate to severe diarrhoea which may eventually lead to death. The parasite impedes growth and development of affected children. A hospital based cross-sectional study was conducted to assess cryptosporidiosis and the associated risk factors among children aged 0-15years attending selected paediatric hospitals in Enugu Metropolis between November 2021 and August 2022. A total of five hundred and fifty stool samples were examined for oocysts of Cryptosporidium species using Formol Ethyl-Acetate sedimentation and modified Ziehl Neelsen’s staining techniques. The overall prevalence of the parasite was 14.4% (79/550). Enugu State University of Science and Technology Teaching Hospital recorded the highest prevalence 32(25.6%) of Cryptosporidium species while St. Patrick Hospital recorded the least 1(1.1%). Public hospitals recorded more infections than private hospitals. The age group ≤ 5years 43(15.8%) recorded the highest prevalence. Males 52(17.1%) were more infected than females 27(10.98%), which was not significant (P>0.05). Children whose parents/caregivers had only primary education 11(26.8%), has the highest prevalence while those whose parents/caregivers had tertiary education 17(8.9%), has the least. Children whose parents/caregivers were farming has the highest prevalence 9(25.0%), while children of civil servants, 40(12.4%) has the least which was not significant (P>0.05). Children living in multifamily residences 48(15.2%) had higher prevalence than those living in private homes, 2(6.3%). Other protozoan parasites identified in the study were Entamoeba histolytica 88(16.1%) and Giardia lamblia 69(12.5%). There were co-infections of Cryptosporidium and Entamoeba histolytica 27(4.9%), Cryptosporidium and Giardia lamblia 21(4.3%) which was not significant (P>0.05). Intervention through health education on good hygiene habits, and provision of clean water and proper disposal of faeces will help reduce cryptosporidiosis among children.
- risk factors
- Enugu Metropolis
How to Cite
Arora DR, Arora, BB. Medical parasitology, 3rd edition New Dellhi. CBS publishers and Distributers pvt. Ltd. 2010:101-104.
OgouyÃ¨mi-Hounto A, Alihonou F, Aholoukpe I, Bagnan L, Orekan J, Sossa B, Zohoun l, Alao J, Gazard DK. Prevalence of cryptosporidiosis infection among children under 5- years in Cotonou, Benin. Parasitology and Vector Biology. 2017;9(6):89-94.
Wellington OC, Teslim O, Oladipo O, Adetayo F, Godswill I. Cryptosporidium and other intestinal protozoans in children with diarrhoea in Lagos, Nigeria. The Internet Journal of Tropical Medicine. 2008;5:2-5
Squire SA, Ryan U. Cryptosporidium and Giardia in Africa: Current and future challenges. Parasite and Vectors. 2017;10(195):1-32.
Centers for Disease Control and Prevention (CDC) Parasites-Cryptosporidium (also known as crypto).
Available:www.cdc.gov/parasites last updated 2019 Access on 12 June 2022.
Messner MJ, Berger P. Cryptosporidium infection risk: Results of new dose-response modeling. Risk Analysis. 2016;36:1969-1982 DOI: 10.1111/risa.12541
Fetene T, Worku N, Huruy K, Kebede N. Cryptosporidium recovered from Musca domestica, Musca sorbens and mango juice accessed by synanthropic flies in Bahirda, Ethiopia. Zoonoses Public Health. 2011;1(58):69-75.
Kotlof KL, Nataro JP, Blackwelder WC, Nasrin D, Farag TH, Panchalingam S, Wu Y, Sow SO, Sur D, Breiman RF, Faruque AS, Zaidi AK, Saha D, Alonso PL, Tamboura B, Sanogo D, Onwuchekwa U, Manna B, Ramamurthy T, Kanungo S, Ochieng JB, Omore R, Oundo JO, Hossain A, Das SK, Ahmed S, Qureshi S, Quadri F, Adegbola RA, Antonio M, Hossain MJ, Akinsola A, Mandomando I, Nhampossa T, Acacio S, Biswas K, O’Reilly CE, Mintz ED, Berkeley LY, Muhsen K, Sommerfelt H, Robins-Browne RM, Levine MM. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study GEMS): A prospective, case-control study. Lancet Public Health. 2013;382:209-222.
Khan A, Shams S, Khan S, Khan MI, Khan S, Ali A. Evaluation of prevalence and risk factors associated with Cryptosporidium infection in rural population of district Buner, Pakistan. Plos One. 2019;14:1.
Burnet JB, Penny C, Ogorzal L, Cauchie HM. Spatial and temporal distribution of cryptosporidium and giardia in a drinking water resource implication for monitoring and risk assessment. Science of the Total Environment. 2014;472:1023-1035.
Khalil IA, Troeger C, Rao PC, Blacker BF, Brown A, Brewer TG. Morbidity, mortality and long-term consequences associated with diarrhea from Cryptosporidium infection in children younger than 5 years: A meta-analyses study. Lancet Public Health. 2018;6:758-768.
Ayuba K, Oti V, Okwoli A, Ioannou M, Chindo I. High prevalence of human gastrointestinal parasitic infections in an Internally Displaced Persons (IDPs) camp in Nasarawa State, Nigeria: A cross-sectional study. South Asian Journal of Parasitology. 2019;1(3):1-8.
Arpit KS, Subra KW, Smith A, Priyadarshi SS. Revisiting the global problem of cryptosporidiosis and recommendations. Tropical Parasitology. 2017;1(7):8-25.
Spickler AR. Cryptosporidiosis. Available:http://www.cfsph.iastate.edu/DiseaseInfo/factsheets.php
Access on 11 November 2021
Widmer G, Carmena D, Kvac M, Chalmers RM, Kissinger JC, Xiao L, Sateriale A, Striepen B, Laurent F, Lacroix-Lamande S, Gargala G, Favennec L. Update on Cryptosporidium spp.: highlights from the seventh international Giardia and Cryptosporidium conference. Parasite. 2020;27:14 DOI: 10.1051/parasite/2020011
Water Aid. Water, Sanitation and Hygiene National Outcome Routine Mapping (WASH NORM).
Access on 10th July 2021
Onyemelukwe NF, Maduakor UC, Uchenna CA, Okongwu U. Prevalence of intestinal parasites among the malnourished children in Enugu, Nigeria. Annual Research and Review in Biology. 2021;7(36):38-46.
Cheesbrough M. Parasitological tests, District Laboratory practice in tropical countries, second edition, Cambridge University Press, Cambridge United Kingdom. 2009;192-207.
Obiukwu MO, Onyido AE, Umeanaeto PU, Okoye UI. Cryptosporidiosis among children attending University of Nigeria Teaching Hospital, Enugu, Nigeria. Nigerian Journal of Parasitology. 2009; 1(30):54-59.
Abdullahi IN, Emeribe AU, Umar K, Adekola HA, Ghamba PE, Faruku N, Onukegbe NB, Okechukwu CE, Babayo A, Amadu DO. Prevalence of Cryptosporidiosis and associated risk factors among patients with acute diarrhea attending Abuja Teaching hospital, Nigeria. Brunei International Medical Journal. 2020;16:49-57.
Abdelhakam G, Tamomh AM, Agena EE, Mohammed A, Suliman ME, Asmaa BO, Sahar AM. Prevalence of cryptosporidiosis among children with diarrhea under five years admitted to Kosti Teaching Hospital, Kosti City, Sudan. Bio Med Central Infectious Disease. 2021;21:349-354.
Tombang AN, Ambe NF, Tanyi PB, Claude NN, Ngandeu MC, Sangwe BN, Ngwene HD, Samuel NC. Prevalence and risk factors associated with cryptosporidiosis among children within the ages 0-5 years attending the limbe regional hospital, southwest region, Cameroon. BioMedical Central Public Health. 2019;19:1144-1154.
Pumipuntu N, Piratae S. Cryptosporidiosis: A zoonotic disease concern. Veterinary World. 2018;(11)5:681-686.
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